Table 2

Median (range) of pre-dosing sugar concentrations by study cohort

USA (N=20)*Peru (N=19)Zambia (N=63)*p Value†
Pre-mannitol (μg/mL)5.2 (0.1 to 17.3)10.8 (0.0 to 29.7)10.3 (0.8 to 40.2)0.046
Pre-rhamnose (μg/mL)0.0 (0.0 to 0.4)0.0 (0.0 to 20.1)0.1 (0.0 to 36.9)0.024
Pre-lactulose (μg/mL)0.0 (0.0 to 4.0)0.5 (0.0 to 19.9)0.1 (0.0 to 86.1)0.043
  • *Pre-dosing sugar data for the U.S. cohort was available for 20 of the 27 participants and for the Zambian cohort in 63 of the 85 participants.

  • †Kruskal-Wallis test.