RT Journal Article SR Electronic T1 PA-574 Prevalence and factors associated with malaria infection in children aged 10 to 23 months in Togo in 2022 JF BMJ Global Health JO BMJ Global Health FD BMJ Publishing Group Ltd SP A97 OP A97 DO 10.1136/bmjgh-2023-EDC.238 VO 8 IS Suppl 10 A1 Tchankoni, Martin Kouame A1 Arikawa, Shino A1 Gbeasor-Komlanvi, Fifonsi Adjidossi A1 Sadio, Arnold Junior A1 Figueroa-Romero, Antia A1 Berne, Mireia LLach A1 González, Raquel A1 Bertran-Cobo, Cesc A1 Saute, Francisco A1 Ekouevi, Didier Koumavi A1 Briand, Valérie A1 Samai, Mohamed A1 Menendez, Clara YR 2023 UL http://gh.bmj.com/content/8/Suppl_10/A97.2.abstract AB Background Intermittent Preventive Treatment in infants (IPTi) is a strategy to prevent malaria in children living in moderate-to-high malaria transmission areas through administration of a full therapeutic course of sulfadoxine-pyrimethamine. MULTIPLY is a multicentric project aiming at implementing IPTi in three sub-Saharan Africa countries. Before IPTi implementation in Togo, we conducted a survey to estimate malaria and Plasmodium infection prevalence in children aged 10 to 23 months (U2).Methods A cross-sectional household survey was conducted in Haho district between Jan- Feb (dry season) 2022. Three-stage cluster random selection was carried out. Vaccination status, insecticide-treated bed net use, and children’s demographic characteristics were collected. Malaria infection was defined as positive malaria rapid diagnostic test and estimated with its 95% confidence interval (CI). A mixed-effects logistic regression model was used to assess factors associated with malaria infection. Survey data was weighted to reflect the sampling design.Results A total of 685 children (51.8% male) were included with a mean age of 17 months. Eight out of ten slept under bed net the night before the interview. The prevalence of Plasmodium infection was 32.1% (95% CI: 28.6–35.7) of which a half had clinical symptoms. In the multivariable model, low educational level of the household head (primary: aOR=1.78 and no formal education: aOR=1.70; p=0.038; ref = secondary or above), presence of more than one under five years children in the household (aOR=1.47; p=0.031) and living at >5 km from the nearest health facility (aOR=1.52; p=0.042) were associated with malaria infection.Conclusion While the survey was conducted in the dry season, one third of U2 children had malaria infection. IPTi can be a promising strategy to reduce malaria burden in this vulnerable population. Strengthening outreach services and more targeted health communication could play an important role in protecting children against malaria.