RT Journal Article SR Electronic T1 YouTube as a source of misinformation on COVID-19 vaccination: a systematic analysis JF BMJ Global Health JO BMJ Global Health FD BMJ Publishing Group Ltd SP e008334 DO 10.1136/bmjgh-2021-008334 VO 7 IS 3 A1 Li, Heidi Oi-Yee A1 Pastukhova, Elena A1 Brandts-Longtin, Olivier A1 Tan, Marcus G A1 Kirchhof, Mark G YR 2022 UL http://gh.bmj.com/content/7/3/e008334.abstract AB Introduction Vaccines for SARS-CoV-2 have been accessible to the public since December 2020. However, only 58.3% of Americans are fully vaccinated as of 5 November 2021. Numerous studies have supported YouTube as a source of both reliable and misleading information during the COVID-19 pandemic. Misinformation regarding the safety and efficacy of COVID-19 vaccines has negatively impacted vaccination intent. To date, the literature lacks a systematic evaluation of YouTube’s content on COVID-19 vaccination using validated scoring tools. The objective of this study was to evaluate the accuracy, usability and quality of the most widely viewed YouTube videos on COVID-19 vaccination.Methods A search on YouTube was performed on 21 July 2021, using keywords ‘COVID-19 vaccine’ on a cleared-cache web browser. Search results were sorted by ‘views’, and the top 150 most-viewed videos were collected and analysed. Duplicate, non-English, non-audiovisual, exceeding 1-hour duration, or videos unrelated to COVID-19 vaccine were excluded. The primary outcome was usability and reliability of videos, analysed using the modified DISCERN (mDISCERN) score, the modified Journal of the American Medical Association (mJAMA) score and the COVID-19 Vaccine Score (CVS).Results Approximately 11% of YouTube’s most viewed videos on COVID-19 vaccines, accounting for 18 million views, contradicted information from the WHO or the Centers for Disease Control and Prevention. Videos containing non-factual information had significantly lower mDISCERN (p<0.001), mJAMA (p<0.01) and CVS (p<0.001) scores compared with videos with factual information. Videos from government sources had higher mJAMA and CVS scores, but averaged three times the ratio of dislikes to likes, while videos containing non-factual information averaged 14 times more likes than dislikes.Conclusion As the COVID-19 pandemic evolves, widespread adoption of vaccination is essential in reducing morbidity, mortality, and returning to some semblance of normalcy. Providing high-quality and engaging health information from reputable sources is essential in addressing vaccine hesitancy.Data sharing not applicable as no datasets generated and/or analysed for this study.