PT - JOURNAL ARTICLE AU - Chalapati Rao AU - Amrit Jose John AU - Ajit Kumar Yadav AU - Mansha Siraj TI - Subnational mortality estimates for India in 2019: a baseline for evaluating excess deaths due to the COVID-19 pandemic AID - 10.1136/bmjgh-2021-007399 DP - 2021 Nov 01 TA - BMJ Global Health PG - e007399 VI - 6 IP - 11 4099 - http://gh.bmj.com/content/6/11/e007399.short 4100 - http://gh.bmj.com/content/6/11/e007399.full SO - BMJ Global Health2021 Nov 01; 6 AB - Background Estimates of excess mortality are required to assess and compare the impact of the COVID-19 pandemic across populations. For India, reliable baseline prepandemic mortality patterns at national and subnational level are necessary for such assessments. However, available data from the Civil Registration System (CRS) is affected by incompleteness of death recording that varies by sex, age and location.Methods Under-reporting of CRS 2019 deaths was assessed for three age groups (< 5 years, 15–59 years and ≥60 years) at subnational level, through comparison with age-specific death rates from alternate sources. Age-specific corrections for under-reporting were applied to derive adjusted death counts by sex for each location. These were used to compute life expectancy (LE) at birth by sex in 2019, which were compared with subnational LEs from the Global Burden of Disease (GBD) 2019 Study.Results A total of 9.92 million deaths (95% UI 9.70 to 10.02) were estimated across India in 2019, about 2.28 million more than CRS reports. Adjustments to under-five and elderly mortality accounted for 30% and 56% of additional deaths, respectively. Adjustments in Bihar, Jharkhand, Madhya Pradesh, Maharashtra, Rajasthan and Uttar Pradesh accounted for 75% of all additional deaths. Adjusted LEs were below corresponding GBD estimates by ≥2 years for males at national level and in 20 states, and by ≥1 year for females in 12 states.Conclusions These results represent the first-ever subnational mortality estimates for India derived from CRS reported deaths, and serve as a baseline for assessing excess mortality from the COVID-19 pandemic. Adjusted life expectancies indicate higher mortality patterns in India than previously perceived. Under-reporting of infant deaths and those among women and the elderly is evident in many locations. Further CRS strengthening is required to improve the empirical basis for local mortality measurement across the country.All data relevant to the study are available from the various references provided in the bibliography or uploaded as supplementary information.