TY - JOUR T1 - Relative efficiency of demand creation strategies to increase voluntary medical male circumcision uptake: a study conducted as part of a randomised controlled trial in Zimbabwe JF - BMJ Global Health JO - BMJ Global Health DO - 10.1136/bmjgh-2021-004983 VL - 6 IS - Suppl 4 SP - e004983 AU - Collin Mangenah AU - Webster Mavhu AU - Diego Cerecero Garcia AU - Chiedza Gavi AU - Polite Mleya AU - Progress Chiwawa AU - Sandra Chidawanyika AU - Getrude Ncube AU - Sinokuthemba Xaba AU - Owen Mugurungi AU - Noah Taruberekera AU - Ngonidzashe Madidi AU - Katherine L Fielding AU - Cheryl Johnson AU - Karin Hatzold AU - Fern Terris-Prestholt AU - Frances M Cowan AU - Sergio Bautista-Arredondo Y1 - 2021/07/01 UR - http://gh.bmj.com/content/6/Suppl_4/e004983.abstract N2 - Background Supply and demand-side factors continue to undermine voluntary medical male circumcision (VMMC) uptake. We assessed relative economic costs of four VMMC demand creation/service-delivery modalities as part of a randomised controlled trial in Zimbabwe.Methods Interpersonal communication agents were trained and incentivised to generate VMMC demand across five districts using four demand creation modalities (standard demand creation (SDC), demand creation plus offer of HIV self-testing (HIVST), human-centred design (HCD)-informed approach, HCD-informed demand creation approach plus offer of HIVST). Annual provider financial expenditure analysis and activity-based-costing including time-and-motion analysis across 15 purposively selected sites accounted for financial expenditures and donated inputs from other programmes and funders. Sites represented three models of VMMC service-delivery: static (fixed) model offering VMMC continuously to walk-in clients at district hospitals and serving as a district hub for integrated mobile and outreach services, (2) integrated (mobile) modelwhere staff move from the district static (fixed) site with their commodities to supplement existing services or to recently capacitated health facilities, intermittently and (3) mobile/outreach model offering VMMC through mobile clinic services in more remote sites.Results Total programme cost was $752 585 including VMMC service-delivery costs and average cost per client reached and cost per circumcision were $58 and $174, respectively. Highest costs per client reached were in the HCD arm—$68 and lowest costs in standard demand creation ($52) and HIVST ($55) arms, respectively. Highest cost per client circumcised was observed in the arm where HIVST and HCD were combined ($226) and the lowest in the HCD alone arm ($160). Across the three VMMC service-delivery models, unit cost was lowest in static (fixed) model ($54) and highest in integrated mobile model ($63). Overall, economies of scale were evident with unit costs lower in sites with higher numbers of clients reached and circumcised.Conclusions There was high variability in unit costs across arms and sites suggesting opportunities for cost reductions. Highest costs were observed in the HCD+HIVST arm when combined with an integrated service-delivery setting. Mobilisation programmes that intensively target higher conversion rates as exhibited in the SDC and HCD arms provide greater scope for efficiency by spreading costs.Trial registration number PACTR201804003064160.Data are available on request. These are financial and economic cost data used to assess efficiency of models of VMMC demand creation and service delivery. They also include deidentified patient data in the form of time and motion observations. ER -