RT Journal Article SR Electronic T1 Child health and the implementation of Community and District-management Empowerment for Scale-up (CODES) in Uganda: a randomised controlled trial JF BMJ Global Health JO BMJ Global Health FD BMJ Publishing Group Ltd SP e006084 DO 10.1136/bmjgh-2021-006084 VO 6 IS 6 A1 Peter Waiswa A1 Flavia Mpanga A1 Danstan Bagenda A1 Rornald Muhumuza Kananura A1 Thomas O’Connell A1 Dorcus Kiwanuka Henriksson A1 Theresa Diaz A1 Florence Ayebare A1 Anne Ruhweza Katahoire A1 Eric Ssegujja A1 Anthony Mbonye A1 Stefan Swartling Peterson YR 2021 UL http://gh.bmj.com/content/6/6/e006084.abstract AB Introduction Uganda’s district-level administrative units buttress the public healthcare system. In many districts, however, local capacity is incommensurate with that required to plan and implement quality health interventions. This study investigates how a district management strategy informed by local data and community dialogue influences health services.Methods A 3-year randomised controlled trial (RCT) comprised of 16 Ugandan districts tested a management approach, Community and District-management Empowerment for Scale-up (CODES). Eight districts were randomly selected for each of the intervention and comparison areas. The approach relies on a customised set of data-driven diagnostic tools to identify and resolve health system bottlenecks. Using a difference-in-differences approach, the authors performed an intention-to-treat analysis of protective, preventive and curative practices for malaria, pneumonia and diarrhoea among children aged 5 and younger.Results Intervention districts reported significant net increases in the treatment of malaria (+23%), pneumonia (+19%) and diarrhoea (+13%) and improved stool disposal (+10%). Coverage rates for immunisation and vitamin A consumption saw similar improvements. By engaging communities and district managers in a common quest to solve local bottlenecks, CODES fostered demand for health services. However, limited fiscal space-constrained district managers’ ability to implement solutions identified through CODES.Conclusion Data-driven district management interventions can positively impact child health outcomes, with clinically significant improvements in the treatment of malaria, pneumonia and diarrhoea as well as stool disposal. The findings recommend the model’s suitability for health systems strengthening in Uganda and other decentralised contexts.Trial registration number ISRCTN15705788.Data are available upon request. Data access for further research can be freely shared with researchers after a formal request through the corresponding author.