TY - JOUR T1 - Antibiotic use for acute respiratory infections among under-5 children in Bangladesh: a population-based survey JF - BMJ Global Health JO - BMJ Global Health DO - 10.1136/bmjgh-2020-004010 VL - 6 IS - 4 SP - e004010 AU - Md Zakiul Hassan AU - Mohammad Riashad Monjur AU - Md Abdullah Al Jubayer Biswas AU - Fahmida Chowdhury AU - Mohammad Abdullah Heel Kafi AU - Jeffrey Braithwaite AU - Adam Jaffe AU - Nusrat Homaira Y1 - 2021/04/01 UR - http://gh.bmj.com/content/6/4/e004010.abstract N2 - Introduction Despite acute respiratory infections (ARIs) being the single largest reason for antibiotic use in under-5 children in Bangladesh, the prevalence of antibiotic use in the community for an ARI episode and factors associated with antibiotic use in this age group are unknown.Methods We analysed nationally representative, population-based, household survey data from the Bangladesh Demographic and Health Survey 2014 to determine the prevalence of antibiotic use in the community for ARI in under-5 children. Using a causal graph and multivariable logistical regression, we then identified and determined the sociodemographic and antibiotic source factors significantly associated with the use of antibiotics for an episode of ARI.Results We analysed data for 2 144 children aged <5 years with symptoms of ARI from 17 300 households. In our sample, 829 children (39%) received antibiotics for their ARI episode (95% CI 35.4% to 42.0%). Under-5 children from rural households were 60% (adjusted OR (aOR): 1.6; 95% CI 1.2 to 2.1) more likely to receive antibiotics compared with those from urban households, largely driven by prescriptions from unqualified or traditional practitioners. Private health facilities were 50% (aOR: 0.5; 95% CI 0.3 to 0.7) less likely to be sources of antibiotics compared with public health facilities and non-governmental organisations. Age of children, sex of children or household wealth had no impact on use of antibiotics.Conclusion In this first nationally representative analysis of antibiotic use in under-5 children in Bangladesh, we found almost 40% of children received antibiotics for an ARI episode. The significant prevalence of antibiotic exposure in under-5 children supports the need for coordinated policy interventions and implementation of clinical practice guidelines at point of care to minimise the adverse effects attributed to antibiotic overuse.Data are available in a public, open access repository. The Demographic and Health Surveys are publicly available to researchers on request. ER -