RT Journal Article SR Electronic T1 Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review JF BMJ Global Health JO BMJ Global Health FD BMJ Publishing Group Ltd SP e003097 DO 10.1136/bmjgh-2020-003097 VO 5 IS 12 A1 Soham Bandyopadhyay A1 Ronnie E Baticulon A1 Murtaza Kadhum A1 Muath Alser A1 Daniel K Ojuka A1 Yara Badereddin A1 Archith Kamath A1 Sai Arathi Parepalli A1 Grace Brown A1 Sara Iharchane A1 Sofia Gandino A1 Zara Markovic-Obiago A1 Samuel Scott A1 Emery Manirambona A1 Asif Machhada A1 Aditi Aggarwal A1 Lydia Benazaize A1 Mina Ibrahim A1 David Kim A1 Isabel Tol A1 Elliott H Taylor A1 Alexandra Knighton A1 Dorothy Bbaale A1 Duha Jasim A1 Heba Alghoul A1 Henna Reddy A1 Hibatullah Abuelgasim A1 Kirandeep Saini A1 Alicia Sigler A1 Leenah Abuelgasim A1 Mario Moran-Romero A1 Mary Kumarendran A1 Najlaa Abu Jamie A1 Omaima Ali A1 Raghav Sudarshan A1 Riley Dean A1 Rumi Kisyova A1 Sonam Kelzang A1 Sophie Roche A1 Tazin Ahsan A1 Yethrib Mohamed A1 Andile Maqhawe Dube A1 Grace Paida Gwini A1 Rashidah Gwokyala A1 Robin Brown A1 Mohammad Rabiul Karim Khan Papon A1 Zoe Li A1 Salvador Sun Ruzats A1 Somy Charuvila A1 Noel Peter A1 Khalil Khalidy A1 Nkosikhona Moyo A1 Osaid Alser A1 Arielis Solano A1 Eduardo Robles-Perez A1 Aiman Tariq A1 Mariam Gaddah A1 Spyros Kolovos A1 Faith C Muchemwa A1 Abdullah Saleh A1 Amanda Gosman A1 Rafael Pinedo-Villanueva A1 Anant Jani A1 Roba Khundkar YR 2020 UL http://gh.bmj.com/content/5/12/e003097.abstract AB Objectives To estimate COVID-19 infections and deaths in healthcare workers (HCWs) from a global perspective during the early phases of the pandemic.Design Systematic review.Methods Two parallel searches of academic bibliographic databases and grey literature were undertaken until 8 May 2020. Governments were also contacted for further information where possible. There were no restrictions on language, information sources used, publication status and types of sources of evidence. The AACODS checklist or the National Institutes of Health study quality assessment tools were used to appraise each source of evidence.Outcome measures Publication characteristics, country-specific data points, COVID-19-specific data, demographics of affected HCWs and public health measures employed.Results A total of 152 888 infections and 1413 deaths were reported. Infections were mainly in women (71.6%, n=14 058) and nurses (38.6%, n=10 706), but deaths were mainly in men (70.8%, n=550) and doctors (51.4%, n=525). Limited data suggested that general practitioners and mental health nurses were the highest risk specialities for deaths. There were 37.2 deaths reported per 100 infections for HCWs aged over 70 years. Europe had the highest absolute numbers of reported infections (119 628) and deaths (712), but the Eastern Mediterranean region had the highest number of reported deaths per 100 infections (5.7).Conclusions COVID-19 infections and deaths among HCWs follow that of the general population around the world. The reasons for gender and specialty differences require further exploration, as do the low rates reported in Africa and India. Although physicians working in certain specialities may be considered high risk due to exposure to oronasal secretions, the risk to other specialities must not be underestimated. Elderly HCWs may require assigning to less risky settings such as telemedicine or administrative positions. Our pragmatic approach provides general trends, and highlights the need for universal guidelines for testing and reporting of infections in HCWs.