RT Journal Article SR Electronic T1 Impact of a health system strengthening intervention on maternal and child health outputs and outcomes in rural Rwanda 2005–2010 JF BMJ Global Health FD BMJ Publishing Group Ltd SP e000674 DO 10.1136/bmjgh-2017-000674 VO 3 IS 2 A1 Dana R Thomson A1 Cheryl Amoroso A1 Sidney Atwood A1 Matthew H Bonds A1 Felix Cyamatare Rwabukwisi A1 Peter Drobac A1 Karen E Finnegan A1 Didi Bertrand Farmer A1 Paul E Farmer A1 Antoinette Habinshuti A1 Lisa R Hirschhorn A1 Anatole Manzi A1 Peter Niyigena A1 Michael L Rich A1 Sara Stulac A1 Megan B Murray A1 Agnes Binagwaho YR 2018 UL http://gh.bmj.com/content/3/2/e000674.abstract AB Introduction Although Rwanda’s health system underwent major reforms and improvements after the 1994 Genocide, the health system and population health in the southeast lagged behind other areas. In 2005, Partners In Health and the Rwandan Ministry of Health began a health system strengthening intervention in this region. We evaluate potential impacts of the intervention on maternal and child health indicators.Methods Combining results from the 2005 and 2010 Demographic and Health Surveys with those from a supplemental 2010 survey, we compared changes in health system output indicators and population health outcomes between 2005 and 2010 as reported by women living in the intervention area with those reported by the pooled population of women from all other rural areas of the country, controlling for potential confounding by economic and demographic variables.Results Overall health system coverage improved similarly in the comparison groups between 2005 and 2010, with an indicator of composite coverage of child health interventions increasing from 57.9% to 75.0% in the intervention area and from 58.7% to 73.8% in the other rural areas. Under-five mortality declined by an annual rate of 12.8% in the intervention area, from 229.8 to 83.2 deaths per 1000 live births, and by 8.9% in other rural areas, from 157.7 to 75.8 deaths per 1000 live births. Improvements were most marked among the poorest households.Conclusion We observed dramatic improvements in population health outcomes including under-five mortality between 2005 and 2010 in rural Rwanda generally and in the intervention area specifically.