You are here

Article Text

Article menu

Download PDFPDF

Abstracts of Poster and e-Poster Presentations
PA-562 Epidemiology of HIV and Helminth co-infection among pulmonary tuberculosis patients at Jamot hospital in Yaoundé, Cameroon
Free
  1. Genevieve Andoseh1,2,
  2. Lionel Ulrich Tiani1,2,3,
  3. Axel Cyriaque Ambassa1,2,
  4. Jean Paul Assam Assam2,4,
  5. Fossi Cedric Tchinda2,
  6. Nkah Leonard Numfor5,
  7. Joseph Kamgno6,7,
  8. Francine Ntoumi8,9,
  9. Véronique Beng Penlap1,2
  1. 1Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon
  2. 2Laboratory for Tuberculosis Research and Pharmacology, Biotechnology Center, Cameroon
  3. 3Laboratory for Vector biology and control, Biotechnology Center, Cameroon
  4. 4Department of Microbiology, University of Yaoundé I, Cameroon
  5. 5Fondation Congolaise pour la Recherche Médicale, Republic of Congo
  6. 6Centre for Research on Filariasis and other Tropical Diseases, Cameroon
  7. 7Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Cameroon
  8. 8Fondation Congolaise pour la Recherche Médicale, Université Marien Gouabi, Republic of Congo
  9. 9Institute for Tropical Medicine, University of Tübingen, Germany

Abstract

Background Tuberculosis (TB), HIV and Helminths are serious overlapping public health problems in sub-Saharan Africa. This triple burden may lead to accelerated disease progression. Although HIV is integrated in TB programs in Cameroon, data on TB-helminth co-infection still remains limited. This study was aimed at determining the prevalence of helminths and their associated factors among pulmonary tuberculosis patients at Jamot hospital in Yaoundé, Cameroon.

Methods This was a cross sectional study conducted at the Jamot hospital in Yaoundé, Cameroon from April 2022 to March 2023 with participants aged 18 years and above. A well designed questionnaire was used to capture sociodemographic data, clinical history and risk factors for TB, HIV and helminth infections. Sputum, stool and blood samples were collected from each consenting participant. Sputum was examined using auramine microscopy. Stool was examined using the kato-katz and Mini-FLOTAC techniques. Blood was used for HIV serology according to guidelines. TB-uninfected healthy controls were also recruited and their blood and stool samples similarly analysed.

Results A total of 321 sputum smear-positive TB patients (72% males and 28% females) and 65 healthy controls (54% males and 46% females) were included in this study. The prevalence of TB-HIV co-infection was 13.4% (43/321). The prevalence of any helminth infection among TB patients was 13.5% (37/274) and 7.7% (5/65) among controls. The most prevalent helminth species in this study was Ascaris lumbricoides (62%, 23/37), followed by Trichuris trichuria (19%, 7/37), Strongyloides stercoralis (5.4%, 2/37), and hookworm (2,7%, 1/37). TB-HIV-Helminth triple co-infection was found in 3 cases.

Conclusion The prevalence of TB-HIV and TB-Helminth co-infection is similar. This emphasizes the fact that diagnosis and treatment of helminth infections should be integrated in TB control programs in Cameroon for a better management of the disease.

https://doi.org/10.1136/bmjgh-2023-EDC.235

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.