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Bridging research integrity and global health epidemiology (BRIDGE) guidelines: explanation and elaboration
  1. Sandra Alba1,
  2. Annick Lenglet2,
  3. Kristien Verdonck3,
  4. Johanna Roth4,
  5. Rutuja Patil5,
  6. Walter Mendoza6,
  7. Sanjay Juvekar5,
  8. Susan F Rumisha7,8
  1. 1 Health, KIT Royal Tropical Insititute, Amsterdam, The Netherlands
  2. 2 Médecins Sans Frontières, Amsterdam, North Holland, The Netherlands
  3. 3 Tropical diseases, Institute of Tropical Medicine, Antwerp, Belgium
  4. 4 European and Developing Countries Clinical Trials Partnership, The Hague, South Holland, The Netherlands
  5. 5 Vadu Rural Health Program, KEM Hospital Research Centre, Pune, Maharashtra, India
  6. 6 United Nations Population Fund, Lima, Peru
  7. 7 National Institute for Medical Research, Dar es Salaam, United Republic of Tanzania
  8. 8 Big Data Institute, University of Oxford, Oxford, Oxfordshire, UK
  1. Correspondence to Dr Sandra Alba; s.alba{at}


Over the past decade, two movements have profoundly changed the environment in which global health epidemiologists work: research integrity and research fairness. Both ought to be equally nurtured by global health epidemiologists who aim to produce high quality impactful research. Yet bridging between these two aspirations can lead to practical and ethical dilemmas. In the light of these reflections we have proposed the BRIDGE guidelines for the conduct of fair global health epidemiology, targeted at stakeholders involved in the commissioning, conduct, appraisal and publication of global health research. The guidelines follow the conduct of a study chronologically from the early stages of study preparation until the dissemination and communication of findings. They can be used as a checklist by research teams, funders and other stakeholders to ensure that a study is conducted in line with both research integrity and research fairness principles. In this paper we offer a detailed explanation for each item of the BRIDGE guidelines. We have focused on practical implementation issues, making this document most of interest to those who are actually conducting the epidemiological work.

  • epidemiology

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  • Handling editor Seye Abimbola

  • Twitter @Ru2ja

  • Contributors JR drafted the section on protocol development, KV on data collection, AL on data management, RP, WM and SJ on dissemination and communication. SA compiled all contributions and finalised the document. SFR reviewed and complemented the first draft. All authors reviewed and approved the final version of this manuscript.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement No data are available.

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