The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves.
The first was associated with a mix of SARS-CoV-2 lineages, while the second and third …

Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth …

… Fourth, too much of the world’s vulnerable population remains unvaccinated at present,
and current vaccines are suboptimal in preventing transmission. Given these challenges in …

Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control.
Comprehensive and timely drug susceptibility determination is critical to inform appropriate …

… South Africa’s fourth COVID-19 wave was driven … be identified by the proxy marker of S-gene
target failure with the TaqPath… on the S-genes of viruses in either the BA.4 or BA.5 lineages. …

Background The feasibility of reducing the population-level incidence of human immunodeficiency
virus (HIV) infection by increasing community coverage of antiretroviral therapy (ART) …

… manufacturer’s instructions. A volume of 0.5 ml of plasma was used for HIV-1 RNA isolation
by high-speed centrifugation followed by lysis of virus particles with a chaotropic agent, and …

… As we look towards SANTHE’s future, and a potential expansion to 3 new partner sites (in
Cameroon, Zimbabwe and Uganda), we have assessed the tools we use, with help from …

An evolving dominance of human immunodeficiency virus type 1 subtype C (HIV-1C) in the
AIDS epidemic has been associated with a high prevalence of HIV-1C infection in the …

The application of genomics technologies to medicine and biomedical research is
increasing in popularity, made possible by new high-throughput genotyping and sequencing …