User profiles for M. Simuyandi

Michelo Simuyandi

Centre for Infectious Disease Research in Zambia
Verified email at cidrz.org
Cited by 718

[HTML][HTML] Impact of antibiotics on gut microbiome composition and resistome in the first years of life in low-to middle-income countries: A systematic review

CC Luchen, M Chibuye, R Spijker, M Simuyandi… - PLoS …, 2023 - journals.plos.org
Background Inappropriate antimicrobial usage is a key driver of antimicrobial resistance (AMR).
Low- and middle-income countries (LMICs) are disproportionately burdened by AMR …

Contribution of maternal immunity to decreased rotavirus vaccine performance in low-and middle-income countries

K Mwila, R Chilengi, M Simuyandi… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
The role of maternal immunity, received by infants either transplacentally or orally from breast
milk, in rotavirus vaccine (RV) performance is evaluated here. Breastfeeding withholding …

[PDF][PDF] Pancreatic cancer.

…, M Bechtold, G Phiri, M Simuyandi, M Madsen… - 2017 - dspace.unza.zm
In 2007, the Cancer Disease Hospital (CDH) was opened as the national referral center for
patients diagnosed with cancer in Zambia. Since inception of the CDH, there has been no …

[HTML][HTML] Association of maternal immunity with rotavirus vaccine immunogenicity in Zambian infants

R Chilengi, M Simuyandi, L Beach, K Mwila… - PloS one, 2016 - journals.plos.org
Introduction Live attenuated oral vaccines against rotavirus (RV) have been shown to be
less efficacious in children from developing countries. Reasons for this disparity are not fully …

Reconstructing the history of maize streak virus strain a dispersal to reveal diversification hot spots and its origin in southern Africa

…, DN Shepherd, S Oluwafemi, M Simuyandi… - Journal of …, 2011 - Am Soc Microbiol
Maize streak virus strain A (MSV-A), the causal agent of maize streak disease, is today one
of the most serious biotic threats to African food security. Determining where MSV-A …

[HTML][HTML] Use of an ETEC Proteome Microarray to Evaluate Cross-Reactivity of ETVAX® Vaccine-Induced IgG Antibodies in Zambian Children

C Mubanga, M Simuyandi, K Mwape, K Chibesa… - Vaccines, 2023 - mdpi.com
Developing a broadly protective vaccine covering most ETEC variants has been elusive. The
most clinically advanced candidate yet is an oral inactivated ETEC vaccine (ETVAX ® ). We …

[HTML][HTML] Safety, tolerability, and immunogenicity of an oral inactivated ETEC vaccine (ETVAX®) with dmLT adjuvant in healthy adults and children in Zambia: An age …

…, N Carlin, J Kaim, B Sjöstrand, M Simuyandi… - Vaccine, 2023 - Elsevier
Background Enterotoxigenic Escherichia coli (ETEC) is an important cause of moderate to
severe diarrhoea in children for which there is no licensed vaccine. We evaluated ETVAX®, …

[HTML][HTML] Performance of machine learning classifiers in classifying stunting among under-five children in Zambia

…, R Chilengi, M Simuyandi, CC Chisenga, M Chirwa… - Children, 2022 - mdpi.com
Stunting is a global public health issue. We sought to train and evaluate machine learning (ML)
classification algorithms on the Zambia Demographic Health Survey (ZDHS) dataset to …

[HTML][HTML] Identification of cholera hotspots in Zambia: A spatiotemporal analysis of cholera data from 2008 to 2017

…, O Chewe, C Chisenga, M Simuyandi… - PLoS neglected …, 2020 - journals.plos.org
The global burden of cholera is increasing, with the majority (60%) of the cases occurring in
sub-Saharan Africa. In Zambia, widespread cholera outbreaks have occurred since 1977, …

[HTML][HTML] Shigella-specific antibodies in the first year of life among Zambian infants: A longitudinal cohort study

CC Chisenga, S Bosomprah, M Simuyandi… - PLoS …, 2021 - journals.plos.org
Introduction Shigellosis, is a leading cause of moderate-to-severe diarrhoea and related
mortality in young children in low and middle income countries (LMICs). Knowledge on …