SETTING AND OBJECTIVE: To investigate the sensitivity of the new interferon-gamma
release assay (IGRA), QuantiFERON®-TB Gold Plus (QFT-Plus), for active TB (used as a …

… Cross-reaction was not observed in this study, but we noted a failure by our gold standard
to detect M. tuberculosis in Capilia test-positive isolates that also contained contaminating …

Background Combination of genotypic assays (Xpert MTB/RIF and MTBDRplus (LiPA) would
be a powerful tool to shorten the time for diagnosis of MDR tuberculosis (TB). However, the …

… Cross-reaction was not observed in this study, but we noted a failure by our gold standard
to detect M. tuberculosis in Capilia test-positive isolates that also contained contaminating …

… First, ART can improve the CD4 cell count profile of a population and therefore decrease
progression from infection with M. tuberculosis to TB disease. Second, HIV-infected individuals …

… We describe the baseline prevalence and risk factors of Mycobacterium tuberculosis (M.
tuberculosis) infection among this cohort and explore the quantitative QFT-Plus interferon …

… to broaden the immune response to the M. tuberculosis antigen with the hope of improving
the assay sensitivity for the detection of M. tuberculosis infection, especially among recent …

… Briefly, a microbiologic diagnosis of active TB was defined as either isolation of M. tuberculosis
in culture or positivity by an M. tuberculosis molecular assay on any specimen source. In …

Interferon-gamma release assays are increasingly used in children to establish evidence of
tuberculosis (TB) infection and to assist in the diagnosis of TB disease. The QuantiFERON-…

Background Success of India’s TB control program relies on rapid case detection, monitoring,
care and treatment of drug resistance. Patients on multidrug resistance (MDR) treatment …