based microfluidics for DNA diagnostics of malaria in low resource underserved rural communities

J Reboud, G Xu, A Garrett, M Adriko… - Proceedings of the …, 2019 - National Acad Sciences
Rapid, low-cost, species-specific diagnosis, based upon DNA testing, is becoming important
in the treatment of patients with infectious diseases. Here, we demonstrate an innovation …

[HTML][HTML] Smartphone-based DNA diagnostics for malaria detection using deep learning for local decision support and blockchain technology for security

…, MA Khalid, I Domingos, AL Michala, M Adriko… - Nature …, 2021 - nature.com
In infectious disease diagnosis, results need to be communicated rapidly to healthcare
professionals once testing has been completed so that care pathways can be implemented. This …

Evaluation of circulating cathodic antigen (CCA) urine-cassette assay as a survey tool for Schistosoma mansoni in different transmission settings within Bugiri District …

M Adriko, CJ Standley, B Tinkitina, EM Tukahebwa… - Acta tropica, 2014 - Elsevier
Diagnosis of schistosomiasis at the point-of-care (POC) is a growing topic in neglected
tropical disease research. There is a need for diagnostic tests which are affordable, sensitive, …

[HTML][HTML] Development of CRISPR/Cas13a-based assays for the diagnosis of schistosomiasis

…, H Sivakumaran, TG Egwang, M Adriko… - …, 2023 - thelancet.com
Background Schistosomiasis is a disease that significantly impacts human health in the
developing world. Effective diagnostics are urgently needed for improved control of this disease. …

[HTML][HTML] Performance of circulating cathodic antigen (CCA) urine-dipsticks for rapid detection of intestinal schistosomiasis in schoolchildren from shoreline …

…, NJS Lwambo, CN Lange, HC Kariuki, M Adriko… - Parasites & vectors, 2010 - Springer
For disease surveillance and mapping within large-scale control programmes, RDTs are
becoming popular. For intestinal schistosomiasis, a commercially available urine-dipstick which …

[HTML][HTML] Schistosoma mansoni Infections in Young Children: When Are Schistosome Antigens in Urine, Eggs in Stool and Antibodies to Eggs First Detectable?

…, M Betson, M Adriko, M Arinaitwe… - PLoS neglected …, 2011 - journals.plos.org
Background In Uganda, control of intestinal schistosomiasis with preventive chemotherapy is
typically focused towards treatment of school-aged children; the needs of younger children …

[HTML][HTML] Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

…, M Adriko, N Holroyd, JP Webster, M Berriman… - Nature …, 2021 - nature.com
Control and elimination of the parasitic disease schistosomiasis relies on mass administration
of praziquantel. Whilst these programmes reduce infection prevalence and intensity, their …

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment

…, A Atuhaire, M Arinaitwe, M Adriko… - Parasitology, 2014 - cambridge.org
During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore
communities, a consistently high malaria prevalence was observed in young children despite …

[HTML][HTML] Intestinal schistosomiasis and giardiasis co-infection in sub-Saharan Africa: can a one health approach improve control of each waterborne parasite …

…, A Atuhaire, M Adriko, M Arianaitwe, M Stewart… - Tropical medicine and …, 2020 - mdpi.com
Both intestinal schistosomiasis and giardiasis are co-endemic throughout many areas of sub-Saharan
Africa, significantly impacting the health of millions of children in endemic areas. …

[HTML][HTML] Low Praziquantel Treatment Coverage for Schistosoma mansoni in Mayuge District, Uganda, Due to the Absence of Treatment Opportunities, Rather Than …

M Adriko, CL Faust, LV Carruthers, A Moses… - Tropical medicine and …, 2018 - mdpi.com
The World Health Organization (WHO) recommends praziquantel mass drug administration (MDA)
to control schistosomiasis in endemic regions. We aimed to quantify recent and …