User profiles for L. E. Downey

Laura E Downey

Imperial College London
Verified email at imperial.ac.uk
Cited by 2543

[HTML][HTML] An introduction to the main types of economic evaluations used for informing priority setting and resource allocation in healthcare: key features, uses, and …

HC Turner, RA Archer, LE Downey… - Frontiers in public …, 2021 - frontiersin.org
Economic evidence is increasingly being used for informing health policies. However, the
underlining principles of health economic analyses are not always fully understood by non-…

[HTML][HTML] National healthcare economic evaluation guidelines: a cross-country comparison

D Sharma, AK Aggarwal, LE Downey… - PharmacoEconomics-Open, 2021 - Springer
Background and Objectives Globally, a number of countries have developed guidelines that
describe the design and conduct of economic evaluations as part of health technology …

[HTML][HTML] The impact of COVID-19 on essential health service provision for noncommunicable diseases in the South-East Asia region: a systematic review

T Gadsden, LE Downey, VDR Vilas… - The Lancet Regional …, 2022 - thelancet.com
Background COVID-19 has had a profound impact on the health systems of the 11 countries
of the WHO South East Asia Region. We conducted a systematic review of studies that used …

Profiles of white matter tract pathology in frontotemporal dementia

…, GR Ridgway, IB Malone, LE Downey… - Human brain …, 2014 - Wiley Online Library
Despite considerable interest in improving clinical and neurobiological characterisation of
frontotemporal dementia and in defining the role of brain network disintegration in its …

Pain and temperature processing in dementia: a clinical and neuroanatomical analysis

PD Fletcher, LE Downey, HL Golden, CN Clark… - Brain, 2015 - academic.oup.com
Symptoms suggesting altered processing of pain and temperature have been described in
dementia diseases and may contribute importantly to clinical phenotypes, particularly in the …

The language profile of behavioral variant frontotemporal dementia

CJD Hardy, AH Buckley, LE Downey… - Journal of …, 2016 - content.iospress.com
Background: The language profile of behavioral variant frontotemporal dementia (bvFTD)
remains to be fully defined. Objective: We aimed to quantify the extent of language deficits in …

[HTML][HTML] Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions

CJ Mahoney, LE Downey, GR Ridgway, J Beck… - Alzheimer's research & …, 2012 - Springer
Introduction Frontotemporal dementia (FTD) is a common cause of early-onset dementia
with a significant genetic component, as underlined by the recent identification of repeat …

[HTML][HTML] White matter tract signatures of the progressive aphasias

…, IB Malone, GR Ridgway, AH Buckley, LE Downey… - Neurobiology of …, 2013 - Elsevier
The primary progressive aphasias (PPA) are a heterogeneous group of language-led
neurodegenerative diseases resulting from large-scale brain network degeneration. White matter (…

Longitudinal diffusion tensor imaging in frontotemporal dementia

…, JM Nicholas, PD Fletcher, LE Downey… - Annals of …, 2015 - Wiley Online Library
Objective Novel biomarkers for monitoring progression in neurodegenerative conditions are
needed. Measurement of microstructural changes in white matter (WM) using diffusion …

[HTML][HTML] Health technology assessment for policy making in India: current scenario and way forward

S Prinja, LE Downey, VK Gauba… - PharmacoEconomics …, 2018 - Springer
The Indian government has made a commitment to achieve Universal Health Coverage (UHC)[1,
2], as a means to reduce catastrophic out-of-pocket health expenditure and ensure …