Randomized, controlled, assessor-blind clinical trial to assess the efficacy of single-versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris trichiura …

…, YJ Honkpehedji, JC Dejon Agobe… - Antimicrobial agents …, 2014 - Am Soc Microbiol
In many regions where soil-transmitted helminth infections are endemic, single-dose albendazole
is used in mass drug administration programs to control infections. There are little data …

Controlled human malaria infection of healthy adults with lifelong malaria exposure to assess safety, immunogenicity, and efficacy of the asexual blood stage malaria …

JC Dejon-Agobe, U Ateba-Ngoa… - Clinical Infectious …, 2019 - academic.oup.com
Background GMZ2 is a recombinant malaria vaccine inducing immune responses against
Plasmodium falciparum (Pf) merozoite surface protein-3 and glutamate-rich protein. We used …

[HTML][HTML] Schistosomiasis in Gabon from 2000 to 2021-A review

JC Dejon-Agobé, JR Edoa, AA Adegnika… - Acta tropica, 2022 - Elsevier
… Although the treatment protocol consisted of three doses of 60 mg per body weight once per
month for three consecutive months, Dejon-Agobé and colleagues, using the egg reduction …

[HTML][HTML] Schistosoma haematobium effects on Plasmodium falciparum infection modified by soil-transmitted helminths in school-age children living in rural areas of …

JC Dejon-Agobe, JF Zinsou… - PLoS neglected …, 2018 - journals.plos.org
Background Malaria burden remains high in the sub-Saharan region where helminths are
prevalent and where children are often infected with both types of parasites. Although the …

[HTML][HTML] Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

JC Dejon-Agobé, JR Edoa, YJ Honkpehedji… - Parasites & vectors, 2019 - Springer
Background Sub-Saharan Africa carries most of the global burden of schistosomiasis. To
optimize disease control and reduce morbidity, precise data are needed for control measures …

Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled …

JF Zinsou, DJ Diemert, JC Dejon-Agobé… - The Lancet Infectious …, 2024 - thelancet.com
Background A human hookworm vaccine is being developed to protect children against iron
deficiency and anaemia associated with chronic infection with hookworms. Necator …

[HTML][HTML] Birth weight, growth, nutritional status and mortality of infants from Lambaréné and Fougamou in Gabon in their first year of life

R Zoleko-Manego, J Mischlinger, JC Dejon-Agobé… - PLoS …, 2021 - journals.plos.org
Background Malnutrition and low birth weight (LBW) are two common causes of morbidity
and mortality among children in sub-Saharan Africa. Both malnutrition and LBW affect early …

[HTML][HTML] Schistosoma haematobium infection is associated with lower serum cholesterol levels and improved lipid profile in overweight/obese individuals

…, YY Honpkehedji, JC Dejon-Agobe… - Plos Neglected …, 2020 - journals.plos.org
Infection with parasitic helminths has been reported to improve insulin sensitivity and glucose
homeostasis, lowering the risk for type 2 diabetes. However, little is known about its impact …

[HTML][HTML] Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

O Nouatin, JB Mengue, JC Dejon-Agobé… - PLoS Neglected …, 2021 - journals.plos.org
Background Helminths can modulate the host immune response to Plasmodium falciparum
and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth …

[HTML][HTML] Epidemiology of schistosomiasis and soil-transmitted helminth coinfections among schoolchildren living in Lambaréné, Gabon

JC Dejon-Agobé, YJ Honkpehedji… - The American journal …, 2020 - ncbi.nlm.nih.gov
Schistosomiasis is a parasitic infection highly prevalent in Central Africa where it is co-endemic
with many other parasitic infections, including soil-transmitted helminths (STHs). For its …