[HTML][HTML] Monkeypox virus in Nigeria: infection biology, epidemiology, and evolution

E Alakunle, U Moens, G Nchinda, MI Okeke - Viruses, 2020 - mdpi.com
Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member
of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years …

[HTML][HTML] Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209+ dendritic cells for immune T cell areas

…, KL Jeffrey, RM Anthony, C Kluger, G Nchinda… - Cell, 2010 - cell.com
Dendritic cells (DCs), critical antigen-presenting cells for immune control, normally derive
from bone marrow precursors distinct from monocytes. It is not yet established if the large …

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

C Trumpfheller, M Caskey, G Nchinda… - Proceedings of the …, 2008 - National Acad Sciences
CD4 + Th1 type immunity is implicated in resistance to global infectious diseases. To improve
the efficacy of T cell immunity induced by human immunodeficiency virus (HIV) vaccines, …

[HTML][HTML] The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

G Nchinda, J Kuroiwa, M Oks… - The Journal of …, 2008 - Am Soc Clin Investig
… (E) CD11c-DTR mice were vaccinated with 30 μg scDEC-OVA or backbone vector and
were depleted of CD11c + DCs 4 days later by injection of 4 ng/g of DT (DT+); then CFSE-labeled …

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody

…, L Bozzacco, Y Do, G Nchinda… - Blood, The Journal …, 2010 - ashpublications.org
… The T-cell response was broad, recognizing at least 3 Gag peptides, and high titers of anti-human
immunoglobulin G antibody were made. Anti-hDEC205 also improved the cross-…

[HTML][HTML] Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas

…, E Phillips, S Mallal, AD De Silva, G Nchinda… - Frontiers in …, 2017 - frontiersin.org
Background Dengue is a major public health problem worldwide. Assessment of adaptive
immunity is important to understanding immunopathology and to define correlates of …

Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus

VV Temchura, M Tenbusch, G Nchinda, G Nabi… - Vaccine, 2008 - Elsevier
Exosomes have been proposed as candidates for therapeutic immunization. The present
study demonstrates that incorporation of the G protein of vesicular stomatitis virus (VSV-G) into …

[HTML][HTML] Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

…, M Tenbusch, G Nchinda, V Temchura, G Nabi… - BMC immunology, 2009 - Springer
Background Targeting of protein antigens to dendritic cells (DC) via the DEC205 receptor
enhances presentation of antigen-derived peptides on MHC-I and MHC-II molecules and, in …

[HTML][HTML] A cross-sectional study of acute dengue infection in paediatric clinics in Cameroon

…, MIM Fumba, ES Massom, G Nchinda… - BMC public health, 2019 - Springer
Background Dengue fever is the world’s fastest spreading mosquito borne viral infection. It
is prevalent throughout both subtropical and tropical region, and affects over 128 countries. …

Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin

A Charalambous, M Oks, G Nchinda… - The Journal of …, 2006 - journals.aai.org
To determine whether strong CD4+ T cell immunity could be induced to a nonmutated self
protein that is important for tumorigenesis, we selectively targeted the xenogeneic form of …