User profiles for E. M. Hodel

Eva Maria Hodel

University of Liverpool
Verified email at liverpool.ac.uk
Cited by 1017

Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation

…, H Pertinez, L Bonnett, EM Hodel… - Journal of …, 2018 - academic.oup.com
Objectives The oxazolidinone linezolid is an effective component of drug-resistant TB treatment,
but its use is limited by toxicity and the optimum dose is uncertain. Current strategies are …

Dolutegravir versus efavirenz in women starting HIV therapy in late pregnancy (DolPHIN-2): an open-label, randomised controlled trial

…, A Colbers, K Byrne, K Seden, EM Hodel… - The Lancet …, 2020 - thelancet.com
Background Late initiation of HIV antiretroviral therapy (ART) in pregnancy is associated
with not achieving viral suppression before giving birth and increased mother-to-child …

A single LC–tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma

EM Hodel, B Zanolari, T Mercier, J Biollaz… - … of Chromatography B, 2009 - Elsevier
Among the various determinants of treatment response, the achievement of sufficient blood
levels is essential for curing malaria. For helping us at improving our current understanding …

[HTML][HTML] Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: a randomised trial (DolPHIN-1 study)

…, A Amara, J Gini, L Else, C Heiburg, EM Hodel… - PLoS …, 2019 - journals.plos.org
Background The global transition to use of dolutegravir (DTG) in WHO-preferred regimens
for HIV treatment is limited by lack of knowledge on use in pregnancy. Here we assessed the …

How robust are malaria parasite clearance rates as indicators of drug effectiveness and resistance?

IM Hastings, K Kay, EM Hodel - Antimicrobial agents and …, 2015 - Am Soc Microbiol
Artemisinin-based combination therapies (ACTs) are currently the first-line drugs for treating
uncomplicated falciparum malaria, the most deadly of the human malarias. Malaria parasite …

[HTML][HTML] Pharmacological considerations in the design of anti-malarial drug combination therapies–is matching half-lives enough?

IM Hastings, EM Hodel - Malaria journal, 2014 - Springer
Anti-malarial drugs are now mainly deployed as combination therapy (CT), primarily as a
mechanism to prevent or slow the spread of resistance. This strategy is justified by …

Prevalence of Potentially Clinically Significant Drug–Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature

D Hodge, EM Hodel, E Hughes… - JAIDS Journal of …, 2023 - journals.lww.com
Background: Contemporary first-line antiretrovirals have considerably reduced liability for
clinically significant drug–drug interactions (DDI). This systematic review evaluates the …

[HTML][HTML] 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study

…, K Seden, A Twimukye, H Theunissen, EM Hodel… - The Lancet …, 2022 - thelancet.com
Background Late initiation of antiretrovirals in pregnancy is associated with increased risk of
perinatal transmission and higher infant mortality. We report the final 72-week postpartum …

[HTML][HTML] Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study

P Pemberton-Ross, TA Smith, EM Hodel, K Kay… - Malaria journal, 2015 - Springer
Effective population-level interventions against Plasmodium falciparum malaria lead to age-shifts,
delayed morbidity or rebounds in morbidity and mortality whenever they are deployed …

[HTML][HTML] Guillain-Barré syndrome following SARS-CoV-2 vaccination in the UK: a prospective surveillance study

…, B Singh, SE Leonhard, EM Hodel… - BMJ neurology …, 2022 - ncbi.nlm.nih.gov
Objective To investigate features of Guillain-Barré syndrome (GBS) following SARS-CoV-2
vaccines and evaluate for a causal link between the two. Methods We captured cases of GBS …