User profiles for E. M. Hodel
Eva Maria HodelUniversity of Liverpool Verified email at liverpool.ac.uk Cited by 1017 |
Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation
Objectives The oxazolidinone linezolid is an effective component of drug-resistant TB treatment,
but its use is limited by toxicity and the optimum dose is uncertain. Current strategies are …
but its use is limited by toxicity and the optimum dose is uncertain. Current strategies are …
Dolutegravir versus efavirenz in women starting HIV therapy in late pregnancy (DolPHIN-2): an open-label, randomised controlled trial
Background Late initiation of HIV antiretroviral therapy (ART) in pregnancy is associated
with not achieving viral suppression before giving birth and increased mother-to-child …
with not achieving viral suppression before giving birth and increased mother-to-child …
A single LC–tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma
Among the various determinants of treatment response, the achievement of sufficient blood
levels is essential for curing malaria. For helping us at improving our current understanding …
levels is essential for curing malaria. For helping us at improving our current understanding …
[HTML][HTML] Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: a randomised trial (DolPHIN-1 study)
Background The global transition to use of dolutegravir (DTG) in WHO-preferred regimens
for HIV treatment is limited by lack of knowledge on use in pregnancy. Here we assessed the …
for HIV treatment is limited by lack of knowledge on use in pregnancy. Here we assessed the …
How robust are malaria parasite clearance rates as indicators of drug effectiveness and resistance?
IM Hastings, K Kay, EM Hodel - Antimicrobial agents and …, 2015 - Am Soc Microbiol
Artemisinin-based combination therapies (ACTs) are currently the first-line drugs for treating
uncomplicated falciparum malaria, the most deadly of the human malarias. Malaria parasite …
uncomplicated falciparum malaria, the most deadly of the human malarias. Malaria parasite …
[HTML][HTML] Pharmacological considerations in the design of anti-malarial drug combination therapies–is matching half-lives enough?
IM Hastings, EM Hodel - Malaria journal, 2014 - Springer
Anti-malarial drugs are now mainly deployed as combination therapy (CT), primarily as a
mechanism to prevent or slow the spread of resistance. This strategy is justified by …
mechanism to prevent or slow the spread of resistance. This strategy is justified by …
Prevalence of Potentially Clinically Significant Drug–Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature
D Hodge, EM Hodel, E Hughes… - JAIDS Journal of …, 2023 - journals.lww.com
Background: Contemporary first-line antiretrovirals have considerably reduced liability for
clinically significant drug–drug interactions (DDI). This systematic review evaluates the …
clinically significant drug–drug interactions (DDI). This systematic review evaluates the …
[HTML][HTML] 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study
Background Late initiation of antiretrovirals in pregnancy is associated with increased risk of
perinatal transmission and higher infant mortality. We report the final 72-week postpartum …
perinatal transmission and higher infant mortality. We report the final 72-week postpartum …
[HTML][HTML] Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study
Effective population-level interventions against Plasmodium falciparum malaria lead to age-shifts,
delayed morbidity or rebounds in morbidity and mortality whenever they are deployed …
delayed morbidity or rebounds in morbidity and mortality whenever they are deployed …
[HTML][HTML] Guillain-Barré syndrome following SARS-CoV-2 vaccination in the UK: a prospective surveillance study
…, B Singh, SE Leonhard, EM Hodel… - BMJ neurology …, 2022 - ncbi.nlm.nih.gov
Objective To investigate features of Guillain-Barré syndrome (GBS) following SARS-CoV-2
vaccines and evaluate for a causal link between the two. Methods We captured cases of GBS …
vaccines and evaluate for a causal link between the two. Methods We captured cases of GBS …