… with primary antibodies for 5–7 d at 37 C with gentle rotation. Samples … d and incubated
with secondary antibodies for 5–7 d at 37 C. Samples were washed with iDISCO wash buffer (1 d…

Background: The regulatory gene pathways that accompany loss of adipose tissue in cancer
cachexia are unknown and were explored using pangenomic transcriptome profiling. …

Results: The average degree of DNA methylation of all analyzed CpG sites was lower in fat
cells from post-obese as compared with never-obese women (P= 0.014). A total of 8504 CpG …

… To investigate whether proteins involved in G1/S transition were altered following GSI
treatment, we analyzed p27Kip1, cyclin D and cyclin E protein levels in these cell lines. We found …

Background Recent genome-wide association (GWA) analyses have identified common
single nucleotide polymorphisms (SNPs) that are associated with obesity. However, the …

… We have analyzed the expression profiles of D. melanogaster S2 cells in which the levels
of individual SWI/SNF subunits have been reduced by RNA interference, and we show that …

… Cells were harvested by carefully scraping the wells after 2 d (M-CSF) or 4 d (Lym-med)
and phenotypic changes or intracellular protein levels of the monocytes were determined by …

Tumor-derived exosomes can modulate the cancer microenvironment and induce metastatic
spread. Exosomes may carry enzymes for leukotriene (LT) biosynthesis, but the role of …

Background Syndecans are proteoglycans whose core proteins have a short cytoplasmic
domain, a transmembrane domain and a large N-terminal extracellular domain possessing …

Objective To assess the efficacy of inhaled ciclesonide in reducing the duration of oxygen
therapy (an indicator of time to clinical improvement) among adults hospitalised with COVID-19…