State-of-the-art in product-service systems
…, JP Angus, M Bastl, A Cousens… - Proceedings of the …, 2007 - journals.sagepub.com
A Product-Service System (PSS) is an integrated combination of products and services. This
Western concept embraces a service-led competitive strategy, environmental sustainability, …
Western concept embraces a service-led competitive strategy, environmental sustainability, …
Human immunology of tuberculosis
Immunology is a central theme when it comes to tuberculosis (TB). The outcome of human
infection with Mycobacterium tuberculosis is dependent on the ability of the immune response …
infection with Mycobacterium tuberculosis is dependent on the ability of the immune response …
The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease
AK Coussens - Photochemical & Photobiological Sciences, 2017 - pubs.rsc.org
The seasonality of infectious disease outbreaks suggests that environmental conditions have
a significant effect on disease risk. One of the major environmental factors that can affect …
a significant effect on disease risk. One of the major environmental factors that can affect …
Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment
AK Coussens, RJ Wilkinson, Y Hanifa… - Proceedings of the …, 2012 - National Acad Sciences
Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …
1α,25‐dihydroxyvitamin D3 inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection
A Coussens, PM Timms, BJ Boucher, TR Venton… - …, 2009 - Wiley Online Library
Matrix metalloproteinases (MMP) can degrade all components of pulmonary extracellular
matrix. Mycobacterium tuberculosis induces production of a number of these enzymes by …
matrix. Mycobacterium tuberculosis induces production of a number of these enzymes by …
High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial
…, TR Venton, KE Barnes, CJ Mullett, AK Coussens… - The Lancet, 2011 - thelancet.com
Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …
Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography
…, KA Wilkinson, CM Graham, AK Coussens… - Nature medicine, 2016 - nature.com
Tuberculosis is classically divided into states of latent infection and active disease. Using
combined positron emission and computed tomography in 35 asymptomatic, antiretroviral-…
combined positron emission and computed tomography in 35 asymptomatic, antiretroviral-…
Champ or chump?: Challenge and threat states during pressurized competition
…, SJ Vine, AH Coussens… - Journal of Sport …, 2013 - journals.humankinetics.com
The present research examined the immediate impact of challenge and threat states on golf
performance in both real competition and a laboratory-based task. In Study 1, 199 …
performance in both real competition and a laboratory-based task. In Study 1, 199 …
[HTML][HTML] Effects of tuberculosis and/or HIV-1 infection on COVID-19 presentation and immune response in Africa
Few studies from Africa have described the clinical impact of co-infections on SARS-CoV-2
infection. Here, we investigate the presentation and outcome of SARS-CoV-2 infection in an …
infection. Here, we investigate the presentation and outcome of SARS-CoV-2 infection in an …
[HTML][HTML] Vitamin D supplementation does not influence SARS-CoV-2 vaccine efficacy or immunogenicity: sub-studies nested within the CORONAVIT randomised …
Vitamin D deficiency has been reported to associate with the impaired development of
antigen-specific responses following vaccination. We aimed to determine whether vitamin D …
antigen-specific responses following vaccination. We aimed to determine whether vitamin D …