Pathogenesis of leptospirosis: the influence of genomics
Leptospirosis is the most widespread zoonosis worldwide and is caused by serovars of
pathogenic Leptospira species. The understanding of leptospiral pathogenesis lags far behind …
pathogenic Leptospira species. The understanding of leptospiral pathogenesis lags far behind …
Genomic surveillance for antimicrobial resistance—a One Health perspective
Antimicrobial resistance (AMR) — the ability of microorganisms to adapt and survive under
diverse chemical selection pressures — is influenced by complex interactions between …
diverse chemical selection pressures — is influenced by complex interactions between …
Prokka: rapid prokaryotic genome annotation
T Seemann - Bioinformatics, 2014 - academic.oup.com
The multiplex capability and high yield of current day DNA-sequencing instruments has made
bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of …
bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of …
From social integration to health: Durkheim in the new millennium
It is widely recognized that social relationships and affiliation have powerful effects on physical
and mental health. When investigators write about the impact of social relationships on …
and mental health. When investigators write about the impact of social relationships on …
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the …
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the …
SNP-sites: rapid efficient extraction of SNPs from multi-FASTA alignments
…, AJ Delaney, J Soares, T Seemann… - Microbial …, 2016 - microbiologyresearch.org
Rapidly decreasing genome sequencing costs have led to a proportionate increase in the
number of samples used in prokaryotic population studies. Extracting single nucleotide …
number of samples used in prokaryotic population studies. Extracting single nucleotide …
Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production
…, JDF Hale, E Vinogradov, T Seemann… - Antimicrobial agents …, 2010 - Am Soc Microbiol
Infections caused by multidrug-resistant (MDR) Gram-negative bacteria represent a major
global health problem. Polymyxin antibiotics such as colistin have resurfaced as effective last-…
global health problem. Polymyxin antibiotics such as colistin have resurfaced as effective last-…
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer
Mycobacterium ulcerans is found in aquatic ecosystems and causes Buruli ulcer in humans,
a neglected but devastating necrotic disease of subcutaneous tissue that is rampant …
a neglected but devastating necrotic disease of subcutaneous tissue that is rampant …
[HTML][HTML] Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR
…, R Robins-Browne, JK Davies, T Seemann… - PLoS …, 2011 - journals.plos.org
… Using a modified t-test p values were calculated and adjusted for multiple testing using false
discovery rate (FDR) correction. A ≥ 1.5-fold change with p<0.05 was considered significant…
discovery rate (FDR) correction. A ≥ 1.5-fold change with p<0.05 was considered significant…
Isolation and rapid sharing of the 2019 novel coronavirus (SARS‐CoV‐2) from the first patient diagnosed with COVID‐19 in Australia
Objectives To describe the first isolation and sequencing of SARS ‐CoV‐2 in Australia and
rapid sharing of the isolate. Setting SARS ‐CoV‐2 was isolated from a 58‐year‐old man from …
rapid sharing of the isolate. Setting SARS ‐CoV‐2 was isolated from a 58‐year‐old man from …