User profiles for S. Niemann

Stefan Niemann

Research Center Borstel
Verified email at fz-borstel.de
Cited by 37000

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

…, G Theron, P van Helden, S Niemann… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis
remains out of control in several parts of the world including Africa and Asia. Although …

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

…, M Schito, J Gardy, DM Cirillo, S Niemann… - NATURE reviews …, 2019 - nature.com
… Whole genome sequencing (WGS) approaches use DNA sequencing platforms to
reconstruct the complete DNA sequence of an organism’s genome. The small (~4.4Mb), single-…

Mechanisms of infective endocarditis: pathogen–host interaction and risk states

K Werdan, S Dietz, B Loeffler, S Niemann… - Nature Reviews …, 2014 - nature.com
… cancer was more common in patients with S. gallolyticus IE than in those with S. gallolyticus
infection at other sites (OR 3.72, 95% CI 2.03–6.81). The virulence characteristics of …

Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis

…, MC Gutierrez, M Fauville, S Niemann… - Journal of clinical …, 2006 - Am Soc Microbiol
… As a general guideline, loci with the highest evolutionary rates within this set may be applied
in the first place, possibly depending on the lineage(s) known to be prevalent in the area of …

[HTML][HTML] Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population …

…, O Narvskaïa, YF Ngeow, L Naumann, S Niemann… - BMC microbiology, 2006 - Springer
… The S lineage which is highly prevalent in Sicily and Sardinia, could be identical to the F28
… T2-Uganda, which was first described by Niemann et al., was repeatedly found in East Africa, …

Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

…, J Mei, L Wei, S Bentley, SR Harris, S Niemann… - Nature …, 2013 - nature.com
Tuberculosis caused 20% of all human deaths in the Western world between the seventeenth
and nineteenth centuries and remains a cause of high mortality in developing countries. In …

Variable host–pathogen compatibility in Mycobacterium tuberculosis

…, S Narayanan, M Nicol, S Niemann… - Proceedings of the …, 2006 - National Acad Sciences
… cases of reactivation of infections acquired in their respective country of origin and that the
genomic deletion profiles of these strains were associated with the respective patient’s place …

[HTML][HTML] High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography

…, PM Small, H Sheffer, S Niemann, S Homolka… - PLoS …, 2008 - journals.plos.org
Mycobacterium tuberculosis infects one third of the human world population and kills
someone every 15 seconds. For more than a century, scientists and clinicians have been …

Mutations in SDHC cause autosomal dominant paraganglioma, type 3

S Niemann, U Müller - Nature genetics, 2000 - nature.com
Nonchromaffin paragangliomas (PGLs) are usually benign, neural-crest–derived, slow-growing
tumours of parasympathetic ganglia. Between 10% and 50% of cases are familial and …

[HTML][HTML] Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

…, S Niemann, K Kremer, JD Ernst, S Gagneux - Nature …, 2010 - nature.com
Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual
hosts for decades. We sequenced the genomes of 21 strains representative of the global …