User profiles for S. Malherbe
Stephanus MalherbeClinical researcher, Stellenbosch University Verified email at sun.ac.za Cited by 2286 |
Lignocellulose biodegradation: fundamentals and applications
S Malherbe, TE Cloete - Reviews in Environmental Science and …, 2002 - Springer
… Therefore, proper management of lignocellulose biodegradation and utilization can serve
to improve the quality of the environment, further man’s understanding of the universe, and …
to improve the quality of the environment, further man’s understanding of the universe, and …
[PDF][PDF] Understanding problem fermentations–a review
… Ethanol inhibits different transport systems utilised by S. cerevisiae (Leao and Van Uden,
1982; Cartwright et al., 1987b; Pascual et al., 1988; Mauricio and Salmon, 1992; Salmon et al …
1982; Cartwright et al., 1987b; Pascual et al., 1988; Mauricio and Salmon, 1992; Salmon et al …
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
… intensified lesion(s), 16 had only intensified lesion(s) and … μl of chloroform and vigorous
mixing for 15 s and then a 2- to 3-… for 30 s, annealing 58 C for 30 s and extension at 72 C for 15 s. …
mixing for 15 s and then a 2- to 3-… for 30 s, annealing 58 C for 30 s and extension at 72 C for 15 s. …
A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes
… A Hedge’s g effect size was then computed to estimate changes in cell subset proportions.
Effect sizes from all individual datasets were integrated into a summary effect size and …
Effect sizes from all individual datasets were integrated into a summary effect size and …
[HTML][HTML] Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial
…, W Brumskine, A Hiemstra, ST Malherbe… - The Lancet Infectious …, 2021 - thelancet.com
Background Targeted preventive therapy for individuals at highest risk of incident tuberculosis
might impact the epidemic by interrupting transmission. We tested performance of a …
might impact the epidemic by interrupting transmission. We tested performance of a …
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs …
Background User-friendly, rapid, inexpensive yet accurate TB diagnostic tools are urgently
needed at points of care in resource-limited settings. We investigated host biomarkers …
needed at points of care in resource-limited settings. We investigated host biomarkers …
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
… We consider the diagnostic tools that could be used to classify an individual’s tuberculosis
state according to the relevant disease dimensions, and the potential benefits of diagnosis …
state according to the relevant disease dimensions, and the potential benefits of diagnosis …
[HTML][HTML] Host blood RNA signatures predict the outcome of tuberculosis treatment
EG Thompson, Y Du, ST Malherbe, S Shankar, J Braun… - Tuberculosis, 2017 - Elsevier
… values were standardized for each sample using a set of reference features, such that: a
b u n d a n c e j = log 2 ( c o u n t s j + 1 ) − ∑ r ∈ r e f s log 2 ( c o u n t s r + 1 ) N r e f s …
b u n d a n c e j = log 2 ( c o u n t s j + 1 ) − ∑ r ∈ r e f s log 2 ( c o u n t s r + 1 ) N r e f s …
[HTML][HTML] RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently
needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature…
needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature…
Diagnostic accuracy of the Cepheid 3-gene host response fingerstick blood test in a prospective, multi-site study: interim results
…, JA Shaw, B Smith, ST Malherbe… - Clinical Infectious …, 2022 - academic.oup.com
Background The development of a fast and accurate, non-sputum-based point-of-care triage
test for tuberculosis (TB) would have a major impact on combating the TB burden worldwide…
test for tuberculosis (TB) would have a major impact on combating the TB burden worldwide…