The increase of allergic diseases in the industrialized world has often been explained by a
decline in infections during childhood. The immunological explanation has been put into the …

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

While successful containment measures of COVID-19 in China and many European countries
have led to flattened curves, case numbers are rising dramatically in other countries, with …

… There was a positive correlation between total IgE and specific IgE (p=0·494, p < 0·0001)
and the concentrations of total IgE were similar in children with positive and negative skin tests. …

… The results of the statistical tests for the overall effect and corresponding p values are presented.
… The results of the statistical tests for the overall effect and corresponding p values are …

… The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)–propeller
domains are the major determinant of resistance has provided opportunities for …

Background The replication-competent recombinant vesicular stomatitis virus (rVSV)–based
vaccine expressing a Zaire ebolavirus (ZEBOV) glycoprotein was selected for rapid safety …

… execution in Gabon; P Garner developed the analytical plan and analysed data; S Gikunda
was responsible for study execution in Kenya; PG Kremsner was the principal investigator in …

Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease (…

Background The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …