Men who have sex with men and HIV/AIDS in sub-Saharan Africa

AD Smith, P Tapsoba, N Peshu, EJ Sanders, HW Jaffe - The Lancet, 2009 - thelancet.com
Globally, men who have sex with men (MSM) continue to bear a high burden of HIV infection.
In sub-Saharan Africa, same-sex behaviours have been largely neglected by HIV research …

[HTML][HTML] Indicators of life-threatening malaria in African children

…, P Winstanley, P Warn, N Peshu… - New England journal …, 1995 - Mass Medical Soc
… Of the 64 children who died, 54 were among those with impaired consciousness (n = 336;
case fatality rate, 11.9 percent) or respiratory distress (n = 251; case fatality rate, 13.9 percent), …

The pathogenesis of severe malaria in African children

…, M English, J Crawley, N Peshu - Annals of Tropical …, 1996 - Taylor & Francis
The pathogenesis of severe, Plasmodium falciparum malaria in African children is considered
in the context of its two major clinical syndromes: malaria with respiratory distress; and …

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

…, OY Sow, RT Grignani, J Sillah, G Sirugo, N Peshu… - Nature …, 2007 - nature.com
Toll-like receptors (TLRs) and members of their signaling pathway are important in the
initiation of the innate immune response to a wide variety of pathogens 1 , 2 , 3 . The adaptor …

Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo-controlled trial

…, F Cutts, K Kawuondo, JN Bulmer, N Peshu… - The Lancet, 1999 - thelancet.com
Background In areas of endemic transmission, malaria in pregnancy is associated with
severe maternal anaemia and low-birthweight babies. We studied the efficacy of intermittent …

[HTML][HTML] Genome-wide and fine-resolution association analysis of malaria in West Africa

…, ME Molyneux, I Mueller, M Parker, N Peshu… - Nature …, 2009 - nature.com
We report a genome-wide association (GWA) study of severe malaria in The Gambia. The
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and a …

A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria

…, I Udalova, AVS Hill, BM Greenwood, N Peshu… - Nature …, 1999 - nature.com
Genetic variation in cytokine promoter regions is postulated to influence susceptibility to
infection, but the molecular mechanisms by which such polymorphisms might affect gene …

[HTML][HTML] Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya

WP O'Meara, P Bejon, TW Mwangi, EA Okiro, N Peshu… - The lancet, 2008 - thelancet.com
Background As efforts to control malaria are expanded across the world, understanding the
role of transmission intensity in determining the burden of clinical malaria is crucial to the …

Profile: the Kilifi health and demographic surveillance system (KHDSS)

…, F Kombe, B Tsofa, K Marsh, N Peshu… - International journal …, 2012 - academic.oup.com
… , Francis Kombe, Benjamin Tsofa, Kevin Marsh, Norbert Peshu, Thomas N Williams, Profile:
The Kilifi Health and Demographic Surveillance System (KHDSS… N Engl J Med … N Engl J Med …

Receptor-specific adhesion and clinical disease in Plasmodium falciparum.

…, A Craig, B Snow, M Msobo, N Peshu… - The American journal …, 1997 - europepmc.org
One important factor in the virulence of infections with Plasmodium falciparum is the adherence
of infected erythrocytes to small vessel endothelium. In infections that lead to serious, life-…