[HTML][HTML] A review of the toxicity and phytochemistry of medicinal plant species used by herbalists in treating people living with HIV/AIDS in Uganda

G Anywar, E Kakudidi, J Mukonzo, A Schubert… - Frontiers in …, 2021 - frontiersin.org
Introduction: Despite concerns about toxicity, potentially harmful effects and herb-drug
interactions, the use of herbal medicines remains widely practiced by people living with HIV/AIDS (…

[HTML][HTML] Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium …

…, A Kapesa, V Baraka, E Konje, B Kidenya, J Mukonzo… - PloS one, 2022 - journals.plos.org
Background Sub-Saharan Africa has the highest burden of malaria in the world. Artemisinin-based
combination therapies (ACTs) have been the cornerstone in the efforts to reduce the …

A novel polymorphism in ABCB1 gene, CYP2B6* 6 and sex predict single‐dose efavirenz population pharmacokinetics in Ugandans

JK Mukonzo, D Röshammar, P Waako… - British journal of …, 2009 - Wiley Online Library
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single‐dose efavirenz
population pharmacokinetics in Ugandans - Mukonzo - 2009 - British Journal of Clinical …

Indigenous traditional knowledge of medicinal plants used by herbalists in treating opportunistic infections among people living with HIV/AIDS in Uganda

…, E Kakudidi, R Byamukama, J Mukonzo… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Currently, more than two thirds of the world's 36.9 million
people living with HIV/AIDS reside in Sub-Saharan Africa. Opportunistic infections (OI) …

Over-the-counter suboptimal dispensing of antibiotics in Uganda

JK Mukonzo, PM Namuwenge, G Okure… - Journal of …, 2013 - Taylor & Francis
Background Overuse and misuse of antibiotics is a serious global problem. While resistance
to older antibiotics is increasing, development of newer molecules has stalled. Resistance …

[HTML][HTML] Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without …

JK Mukonzo, A Okwera, N Nakasujja, H Luzze… - BMC infectious …, 2013 - Springer
Background HIV infection, anti-tuberculosis and efavirenz therapy are associated with
neuropsychological effects. We evaluated the influence of rifampicin cotreatment, efavirenz …

Medicinal plants used by traditional medicine practitioners to boost the immune system in people living with HIV/AIDS in Uganda

…, E Kakudidi, R Byamukama, J Mukonzo… - European Journal of …, 2020 - Elsevier
Introduction People living with HIV/AIDS (PLHIV) widely use medicinal plants for boosting
immunity and managing infections. The aim of this study was to document the medicinal plant …

[HTML][HTML] Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes

JK Mukonzo, JS Owen, J Ogwal-Okeng, RB Kuteesa… - PloS one, 2014 - journals.plos.org
Background Pharmacogenetics contributes to inter-individual variability in pharmacokinetics
(PK) of efavirenz (EFV), leading to variations in both efficacy and toxicity. The purpose of …

[HTML][HTML] A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV …

KR Bisaso, SA Karungi, A Kiragga, JK Mukonzo… - BMC medical informatics …, 2018 - Springer
… For any task, if the patient’s predicted probability was above the obtained J-statistic, viral
suppression was predicted to occur therefore the J-statistic was considered the decision …

[HTML][HTML] Potential drug–drug interactions between antiretroviral therapy and treatment regimens for multi-drug resistant tuberculosis: Implications for HIV care of MDR …

J Mukonzo, E Aklillu, V Marconi, RF Schinazi - International Journal of …, 2019 - Elsevier
HIV-positive TB co-infected patients are at increased risk of multidrug-resistant (MDR)-TB
compared to HIV-negative patients. Co-treatment of MDR-TB and HIV is common particularly in …