Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

…, J Held, CL Calle, JB Mengue, T Gebru, J Ibáñez… - Nature, 2017 - nature.com
A highly protective malaria vaccine would greatly facilitate the prevention and elimination of
malaria and containment of drug-resistant parasites 1 . A high level (more than 90%) of …

[HTML][HTML] DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

…, S Brückner, C Nguetse, J Mengue… - The Lancet Infectious …, 2017 - thelancet.com
Background A drug for causal (ie, pre-erythrocytic) prophylaxis of Plasmodium falciparum
malaria with prolonged activity would substantially advance malaria control. DSM265 is an …

[HTML][HTML] Impact of sickle cell trait and naturally acquired immunity on uncomplicated malaria after controlled human malaria infection in adults in Gabon

…, J Honkpehedji, J Zinsou, JB Mengue… - The American journal …, 2018 - ncbi.nlm.nih.gov
Controlled human malaria infection (CHMI) by direct venous inoculation (DVI) with 3,200
cryopreserved Plasmodium falciparum sporozoites (PfSPZ) consistently leads to parasitemia …

Entropy and variational principle for one-dimensional lattice systems with a general a priori probability: positive and zero temperature

AO Lopes, JK Mengue, J Mohr… - Ergodic Theory and …, 2015 - cambridge.org
… Let µ be a Gibbs measure and B the normalized potential associated to µ, if we call J = e−B,
we have an equivalent definition of entropy given by … We point out that J = e−B does not …

[HTML][HTML] Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

O Nouatin, JB Mengue, JC Dejon-Agobé… - PLoS Neglected …, 2021 - journals.plos.org
Background Helminths can modulate the host immune response to Plasmodium falciparum
and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth …

AQ-13-an investigational antimalarial drug

JB Mengue, J Held, A Kreidenweiss - Expert opinion on …, 2019 - Taylor & Francis
Introduction: AQ-13 is a drug candidate in development for the treatment of Plasmodium
falciparum infections. The chemical structure is similar to chloroquine, a 4-aminoquinoline, with …

On information gain, Kullback-Leibler divergence, entropy production and the involution kernel

AO Lopes, JK Mengue - arXiv preprint arXiv:2003.02030, 2020 - arxiv.org
… On the other hand, if J is a ˆν−Jacobian and it does not assume the value zero, then c = log(…
We suppose that π ≪ ˆν dQ and we denote by J its Radon-Nikodyn derivative. Then, for any …

On the selection of subaction and measure for a subclass of potentials defined by P. Walters

AT Baraviera, AO Lopes, JK Mengue - Ergodic Theory and …, 2013 - cambridge.org
Suppose σ is the shift acting on Bernoulli space X={0, 1} N, and consider a fixed function f: X→
R satisfying the Walters conditions (defined in [P. Walters. A natural space of functions for …

Selection of measure and a large deviation principle for the general one-dimensional XY model

AO Lopes, JK Mengue - Dynamical Systems, 2014 - Taylor & Francis
… For any cylinder where each I j is a closed interval of , we have For any cylinder where
each I j is a open interval of , we have … Let n 0 be such that for j ≥ n 0 , we have . Then, for …

Duality theorems in ergodic transport

AO Lopes, JK Mengue - Journal of Statistical Physics, 2012 - Springer
We analyze several problems of Optimal Transport Theory in the setting of Ergodic Theory.
In a certain class of problems we consider questions in Ergodic Transport which are …