User profiles for E. Kestelyn

Evelyne Kestelyn

Head of Clinical Trials Unit, Oxford University
Verified email at oucru.org
Cited by 4143

The natural history and transmission potential of asymptomatic severe acute respiratory syndrome coronavirus 2 infection

…, NTH Ny, NTT Hong, E Kestelyn… - Clinical Infectious …, 2020 - academic.oup.com
… Since we enrolled patients who had a confirmed diagnosis by 2 independent RT-PCRs (Egene
and RdRp assays) as per the WHO recomendation [16], we used E gene assay for …

[HTML][HTML] Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults

…, RB Geskus, NTT Thuong, E Kestelyn… - … England Journal of …, 2023 - Mass Medical Soc
Background Adjunctive glucocorticoids are widely used to treat human immunodeficiency
virus (HIV)–associated tuberculous meningitis despite limited data supporting their safety and …

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

…, JN Day, L Ly, DDA Thu, L Merson, E Kestelyn… - Elife, 2018 - elifesciences.org
Adjunctive dexamethasone reduces mortality from tuberculous meningitis (TBM) but not
disability, which is associated with brain infarction. We hypothesised that aspirin prevents TBM-…

[HTML][HTML] Living situation affects adherence to combination antiretroviral therapy in HIV-infected adolescents in Rwanda: a qualitative study

PR Mutwa, JI Van Nuil, B Asiimwe-Kateera, E Kestelyn… - PloS one, 2013 - journals.plos.org
Introduction Adherence to combination antiretroviral therapy (cART) is vital for HIV-infected
adolescents for survival and quality of life. However, this age group faces many challenges to …

High human immunodeficiency virus incidence in a cohort of Rwandan female sex workers

SL Braunstein, CM Ingabire, E Kestelyn… - Sexually transmitted …, 2011 - journals.lww.com
Background: Measurement of human immunodeficiency virus (HIV) incidence among female
sex workers in Rwanda is a key part of preparing for HIV prevention trials. Methods: HIV-…

An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis

…, GE Thwaites, D Krysan, LTH Tai, E Kestelyn… - Elife, 2021 - elifesciences.org
Background: Cryptococcal meningitis has high mortality. Flucytosine is a key treatment but
is expensive and rarely available. The anticancer agent tamoxifen has synergistic anti-…

[HTML][HTML] The epidemiology of human papillomavirus infection in HIV-positive and HIV-negative high-risk women in Kigali, Rwanda

…, C Ingabire, J Ntirushwa, E Kestelyn… - BMC infectious …, 2011 - Springer
Background The prevalence, incidence and persistence of human papillomavirus (HPV)
types in sub-Saharan Africa are not well established. The objectives of the current study are to …

[HTML][HTML] Contraceptive rings promote vaginal lactobacilli in a high bacterial vaginosis prevalence population: a randomised, open-label longitudinal study in Rwandan …

…, J van de Wijgert, S Agaba, J Buyze, E Kestelyn… - PLoS …, 2018 - journals.plos.org
Background Hormonal contraception has been associated with a reduced risk of vaginal
dysbiosis, which in turn has been associated with reduced prevalence of sexually transmitted …

Effectiveness of continuous endotracheal cuff pressure control for the prevention of ventilator-associated respiratory infections: An open-label randomized, controlled …

…, J Campbell, E Ahmadnia, E Kestelyn… - Clinical Infectious …, 2022 - academic.oup.com
Background An endotracheal tube cuff pressure between 20 and 30 cmH 2 O is recommended
to prevent ventilator-associated respiratory infection (VARI). We aimed to evaluate …

[HTML][HTML] Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; …

…, J Koirala, S Basnet, E Kestelyn… - The Lancet Child & …, 2024 - thelancet.com
Background Paediatric multisystem inflammatory syndrome temporally associated with
SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children (MIS-C) …