[HTML][HTML] Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients

…, A Soriano, JC Hurtado, C Subirà, B Grau-Pujol… - PloS one, 2020 - journals.plos.org
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively
reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared …

Frequency and distribution of neglected tropical diseases in Mozambique: a systematic review

B Grau-Pujol, M Massangaie, J Cano… - Infectious diseases of …, 2019 - mednexus.org
Background: Neglected tropical diseases (NTDs) affect more than one billion people living
in vulnerable conditions. In spite of initiatives recently contributing to fill NTDs gaps on …

[HTML][HTML] Pre-exposure prophylaxis with hydroxychloroquine for COVID-19: a double-blind, placebo-controlled randomized clinical trial

B Grau-Pujol, D Camprubí-Ferrer, H Marti-Soler… - Trials, 2021 - Springer
Background Pre-exposure prophylaxis (PrEP) is a promising strategy to break COVID-19
transmission. Although hydroxychloroquine was evaluated for treatment and post-exposure …

[HTML][HTML] Towards soil-transmitted helminths transmission interruption: the impact of diagnostic tools on infection prediction in a low intensity setting in Southern …

B Grau-Pujol, H Martí-Soler, V Escola… - PLoS Neglected …, 2021 - journals.plos.org
World Health Organization goals against soil-transmitted helminthiases (STH) are pointing
towards seeking their elimination as a public health problem: reducing to less than 2% the …

Anti-V3/glycan and anti-MPER neutralizing antibodies, but not anti-V2/glycan site antibodies, are strongly associated with greater anti-HIV-1 neutralization breadth …

…, M Schomaker, F Abrahams, B Grau Pujol… - Journal of …, 2015 - Am Soc Microbiol
… We explored changes in neutralization breadth (A) and potency (B) based upon target
mapping of the neutralizing antibodies in each serum. The groups that were compared are …

[HTML][HTML] Single-nucleotide polymorphisms in the beta-tubulin gene and its relationship with treatment response to albendazole in human soil-transmitted helminths in …

B Grau-Pujol, J Gandasegui, V Escola… - The American Journal …, 2022 - ncbi.nlm.nih.gov
Soil-transmitted helminth (STH) cornerstone control strategy is mass drug administration (MDA)
with benzimidazoles. However, MDA might contribute to selection pressure for …

Plasmodium falciparum and helminth coinfections increase IgE and parasite-specific IgG responses

R Santano, R Rubio, B Grau-Pujol, V Escola… - Microbiology …, 2021 - Am Soc Microbiol
Coinfection with Plasmodium falciparum and helminths may impact the immune response to
these parasites because they induce different immune profiles. We studied the effects of …

[HTML][HTML] Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol …

B Grau-Pujol, D Camprubí, H Marti-Soler… - Trials, 2020 - Springer
Objectives The aim of this study is to assess the efficacy of the use of pre-exposure prophylaxis
(PrEP) with hydroxychloroquine against placebo in healthcare workers with high risk of …

[HTML][HTML] Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus …

J Gandasegui, B Grau-Pujol, M Cambra-Pelleja… - Parasites & vectors, 2021 - Springer
Background There is an urgent need for an extensive evaluation of benzimidazole efficacy
in humans. In veterinary science, benzimidazole resistance has been mainly associated with …

[HTML][HTML] Task Force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022

B Grau-Pujol, JV Martins, I Goncalves… - …, 2023 - eurosurveillance.org
On 5 April 2022, the United Kingdom reported an increase of cases of severe acute hepatitis
of unknown aetiology in children, several needing hospitalisation and some required liver …