The majority of the world's population lives in urban areas, and regions with the highest
under-five mortality rates are urbanising rapidly. This 7-year interrupted time series study …

Background Spatial and temporal heterogeneities in the risk of malaria have led the WHO to
recommend fine-scale stratification of the epidemiological situation, making it possible to set …

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection
against Plasmodium falciparum malaria, but the precise nature of the protective effect has …

Background Modelling malaria parasitaemia as function of fever has been proposed as best
alternative to estimate the attributable fraction of malaria fever and the sensitivity and …

Purpose: Cerebral malaria (CM) is suspected to be a potential cause of epilepsy in tropical
areas, but little information is available. The purpose of this study was to evaluate the role of …

Background The pathogenic mechanisms of cerebral malaria (CM) are unclear but are
thought to involve cytokine-mediated inflammation enhanced by parasite sequestration in …

Malaria is a major health burden in sub-Saharan African countries, including Mali. The
disease is complex, with multiple genetic determinants influencing the observed variation in …

Background In order to detect potential disease clusters where a putative source cannot be
specified, classical procedures scan the geographical area with circular windows through a …

The aim of this case-control study was to identify epidemiological risk factors for severe
malaria among children living in Bamako, a malaria-endemic area. For this, 260 healthy …

Background Severe malaria (SM) due to Plasmodium falciparum causes millions of child
deaths in sub-Saharan Africa. It comprises a variety of clinical disorders, including cerebral …