Enterovirus 71 maternal antibodies in infants, Taiwan

Emerg Infect Dis. 2009 Apr;15(4):581-4. doi: 10.3201/eid1504.081550.

Abstract

Enterovirus 71 (EV71) causes life-threatening disease outbreaks in young children in Asia. This cohort study was conducted to understand the dynamics of maternal EV71 antibodies in Taiwanese young infants. Approximately 50% of neonates had detectable EV71 neutralizing antibodies, which declined to almost undetectable levels by 6 months of age.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Antibodies, Viral / blood*
  • Cohort Studies
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / immunology*
  • Disease Outbreaks
  • Enterovirus A, Human / immunology*
  • Enterovirus Infections / epidemiology*
  • Enterovirus Infections / immunology*
  • Female
  • Humans
  • Immunity, Maternally-Acquired*
  • Infant
  • Infant, Newborn
  • Neutralization Tests
  • Pregnancy
  • Prospective Studies
  • Seroepidemiologic Studies
  • Taiwan / epidemiology

Substances

  • Antibodies, Viral