Table 3

Cox proportional hazards model of association between baseline characteristics and attrition from care

	Univariate analysis, HR^ of attrition (95% CI)	Multivariate analysis, HR^ of attrition (95% CI)
Health facility
Ayder Hospital (university hospital)	Reference	Reference
Alamata Health Centre (health centre)	2.18 (1.28 to 3.71)*	2.02 (1.80 to 2.27)**
Alamata Hospital (general hospital)	2.90 (1.62 to 5.19)	2.81 (2.48 to 3.19)
Mekelle Health Centre (health centre)	2.08 (1.25 to 3.46)	2.09 (1.82 to 2.39)
Mehoni Hospital (primary hospital)	1.95 (1.18 to 3.20)	2.06 (1.86 to 2.28)
Mekelle Hospital (health centre)	2.18 (1.20 to 3.98)	2.15 (2.00 to 2.32)
Michew Hospital (general hospital)	2.27 (1.17 to 4.41)	2.00 (1.68 to 2.39)
Gender
Female	Reference	Reference
Male	1.51 (1.16 to 1.95)*	1.34 (1.04 to 1.74)**
Age (years)
14–25	Reference	–
26–50	0.94 (0.66 to 1.33)
>50	1.11 (0.63 to 1.96)
Educational status
No education	Reference	–
Primary	1.02 (0.75 to 1.38)
Secondary	1.11 (0.77 to 1.59)
Tertiary	0.99 (0.61 to 1.60)
Religion
Orthodox Christian	Reference	–
Other religions	1.05 (0.69 to 1.59)
BMI (kg/m²)
18.6–25	Reference	Reference
≤18.5	1.67 (1.28 to 2.17)*	1.40 (0.99 to 1.98)
>25	0.69 (0.34 to 1.42)	0.79 (0.32 to 1.98)
Clinical stage
WHO I–II	Reference	Reference
WHO III–IV	1.30 (1.01 to 1.69)*	1.10 (0.77 to 1.58)
Active TB
No	Reference	Reference
Yes	1.93 (1.33 to 2.80)*	1.39 (0.92 to 2.10)
Initial treatment regimen
Efavirenz-based	Reference	–
Nevirapine-based	1.17 (0.80 to 1.73)
CD4 count (cells/µL)
≥200	Reference	Reference
<200	1.68 (1.29 to 2.19)*	1.48 (1.10 to 1.99)^**;§
Haemoglobin (g/dL)
>10	Reference	Reference
≤10	1.40 (0.98 to 2.13)*	1.40 (0.96 to 2.04)§

**p Value <0.05.
^Hazard ratios estimated using robust sandwich estimators for variance to account for within-HF correlation.
*p Value <0.2.
§HR adjusted for interaction term between CD4 count and haemoglobin value