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Trends and level of control of hypertension among adults attending an ambulatory HIV clinic in Kampala, Uganda: a retrospective study
  1. Robert Kalyesubula1,2,
  2. Alex Kayongo1,
  3. Fred Collins Semitala1,3,
  4. Asaph Muhanguzi3,
  5. Nehemiah Katantazi3,
  6. Dieter Ayers4,
  7. Jamie I Forrest4,5,
  8. Edward J Mills4,6
  1. 1Department of Medicine, Makerere University College of Health Sciences (MakCHS), Kampala, Uganda
  2. 2Department of Physiology, Makerere University College of Health Sciences (MakCHS), Kampala, Uganda
  3. 3Makerere University Joint AIDS Programme, Kampala, Uganda
  4. 4Precision Global Health, Vancouver, British Columbia, Canada
  5. 5School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada
  6. 6Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
  1. Correspondence to Dr Alex Kayongo; alexkayongo{at}gmail.com

Abstract

Background With an ageing HIV-positive population, sub-Saharan Africa is now facing a dual epidemic of communicable and non-communicable diseases (NCDs). This study aimed to assess trends in the prevalence of hypertension and factors associated with hypertension, among adults attending an ambulatory HIV clinic in Kampala, Uganda.

Methods We conducted a retrospective chart review to identify patients with hypertension. We used a random number generator to select 400 patient charts from each year from 2009 to 2014. Blood pressure, age, body mass index (BMI), WHO disease stage and Karnofsky scores were extracted. Logistic regression was used to estimate the strength of the association between each of these factors and the presence of hypertension.

Results In total, 1996 charts were included in this analysis. The mean age of participants was 31 years and 1311/1996 (65.7%) were female. The overall prevalence of hypertension was 418/1996 (20.9%). This rose from 16.9% in 2009 to 32.3% in 2013. Of the patients with hypertension, 96/418 (23.0%) were receiving adequate treatment. Patients >50 years of age had 3.12 times the odds of hypertension compared with patients aged 20–29 years (95% CI 2.00 to 4.85). Men had 1.65 times the odds of hypertension compared with women (95% CI 1.34 to 2.03) and patients with a BMI of 35–39 kg/m2 had 3.93 times the odds of hypertension compared with patients with a BMI <25 kg/m2.

Conclusions The prevalence of hypertension is rising in the Ugandan HIV-positive population. There remains inadequate management and control of hypertension in this group highlighting the need to better integrate NCD care within the HIV clinical settings.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Footnotes

  • Handling editor Soumitra Bhuyan

  • Contributors RK and AK conceived of the study. FCS, AM and NK collected the data. DA and JIF conducted the analyses. EJM supervised the study. All authors contributed to the manuscript and approved the final draft for submission.

  • Competing interests None declared.

  • Ethics approval Research Ethics Review Board, School of Biomedical Sciences, Makerere University, Uganda.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.